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Particularly useful for determining ancient migration and, if compared to another sample, establishing maternal genealogical lineages.
The participant collects DNA using our convenient GeneSwab Collection Kit and then sends that sample to our laboratory. The laboratory sequences an area of the person’s mitochondrial DNA over 400 base pairs long. The sequence is then compared to a standard index to indicate the person’s long distance heritage or, if compared to another, to indicate how closely the two individuals are related.
mtDNA sequencing provides researchers (i.e., forensic scientists, evolutionary biologists, genealogists, and anthropologists) a useful tool for studying human migration patterns, evolution, maternally linked relationships and identification.
There are 2 regions of the mtDNA that are of particular interest to researchers because of their variability among the different human populations. These regions are most commonly referred to as HVR1 and HVR2.
To characterize the HVR1 and HVR2 mtDNA pattern, the DNA is sequenced. GeneTree DNA Testing Center provides mtDNA sequence data and comparative analysis through examining these regions, and reporting the differences as compared to a standard, the Cambridge Reference Sequence.
GeneTree DNA Testing Center uses this service to facilitate in reconstructing family maternal-linked relationships, but the data can also be used to research your own mtDNA sequence. There are a number of publications that will assist you with researching your mtDNA profile and how it relates to published mtDNA migration patterns. Contact us if you are interested in receiving a list of publications that will assist you with your research.
mtDNA Comparative Analysis
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